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Human XCL2 Protein (His Tag)

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Human XCL2 Protein Product Information
Synonym:SCM-1b, SCM1B, SCYC2
Protein Construction:A DNA sequence encoding the human XCL2 (Q9UBD3) (Met 1-Gly 114) was fused with a polyhistidine tag at the C-terminus.
Expressed Host:Baculovirus-Insect Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human XCL2 Protein QC Testing
Purity:> 90 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Val 22
Molecule Mass:The secreted recombinant human XCL2 comprises 103 amino acids and has a predicted molecular mass of 11.7 kDa. The apparent molecular mass of rh XCL2 is approximately 18-20 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human XCL2 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Other XCL2 Recombinant Protein Products
XCL2 Background

XCL2 is a small cytokine belonging to the XC chemokine family. Chemokines are a group of cytokines. Members of this group of so-called C-Chemokines belong to the SCY family of cytokines and are designated XCL (L for ligand) followed by a number. XCL2 is the new designation of SCM-1-beta. XCL2 is highly related to another chemokine called XCL1. XCL2 gene is located on chromosome 1 in humans. XCL2 is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1. XCL2 gene has been proposed to participate in pathways (Chemokine signaling pathway, Cytokine-cytokine receptor interaction) and processes (blood circulation, signal transduction, chemotaxis, immune response). XCL2 are expected to have molecular function (chemokine activity) and to localize in various compartments (extracellular space, extracellular region). A putative protein interactor has been described (XCR1). The spliced mRNA putatively encodes a good protein, containing small cytokines (intecrine / chemokine), interleukin-8 like domain; the complete protein appears to be secreted.

Human XCL2 References
  • Kennedy J, et al. (1995) Molecular cloning and functional characterization of human lymphotactin. J Immunol. 155(1):203-9.
  • Yoshida T, et al. (1998) Identification of single C motif-1 / lymphotactin receptor XCR. J Biol Chem. 273(26):16551-54.
  • Yoshida T, et al. (1996) Structure and expression of two highly related genes encoding SCM-1 / human lymphotactin. FEBS Lett. 395(1):82-8.
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    Catalog: 13502-H08B-10
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    • Human XCL2 Protein (His Tag) SDS-PAGE
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