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Human VSTM1 Protein (Fc Tag)

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VSTM1Protein Product Information
Synonym:UNQ3033, PRO9835, MGC119160, MGC119161, SIRL1, UNQ3033
Protein Construction:A DNA sequence encoding the human VSTM1 (Q6UX27-16) extracellular domain (Met 1-Thr 135) was fused with the Fc region of human IgG1 at the C-terminus.
Species:Human
Expressed Host:Human Cells
Form & Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
VSTM1Protein QC Testing
Purity:> 90 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Tyr 17
Molecule Mass:The recombinant human VSTM1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 360 amino acids and has a predicted molecular mass of 40.6 kDa. The apparent molecular mass of the reduced monomer is approximately 50-60 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
VSTM1Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
13171-H02H
Background

V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds of protein families, including immunoglobulin light and heavy chains, several T-cells such as CD2, CD4, CD80, and CD86, myelin membrane adhesion molecules, junction adhesion molecules (JAM), tyrosine-protein kinase receptors, and the programmed cell death protein1.

References
  • Satow Y, et al. (1986) Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A. J Mol Biol. 190 (4): 593-604.
  • Rees DC, et al. (2009) ABC transporters: the power to change. Cell Biol. 10 (3): 218-227.
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    • Human VSTM1 Protein (Fc Tag) SDS-PAGE
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