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IBA1 / AIF1 Antibody, Mouse MAb

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Human AIF1 Antibody Product Information
Immunogen:Recombinant Human IBA1 / AIF1 protein (Catalog#14227-H07E)
Clone ID:05
Ig Type:Mouse IgG2a
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IBA1 / AIF1 (rh IBA1 / AIF1; Catalog#14227-H07E; P55008-1; Met1-Pro147). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
Human AIF1 Antibody Usage Guide
Specificity:Human IBA1 / AIF1
No cross-reactivity in ELISA with
E.coli cell lysate
Application:ELISA

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human IBA1 / AIF1. The detection limit for Human IBA1 / AIF1 is approximately 0.078 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other AIF1 Antibody Products
IBA1/AIF1 Background

AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"