|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat CLU ORF mammalian expression plasmid, C-GFPSpark tag||RG81601-ACG|
|Rat CLU ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG81601-ACR|
|Rat CLU ORF mammalian expression plasmid, C-Flag tag||RG81601-CF|
|Rat CLU ORF mammalian expression plasmid, C-His tag||RG81601-CH|
|Rat CLU ORF mammalian expression plasmid, C-Myc tag||RG81601-CM|
|Rat CLU ORF mammalian expression plasmid, C-HA tag||RG81601-CY|
|Rat CLU Gene cDNA clone plasmid||RG81601-G|
|Rat CLU ORF mammalian expression plasmid, N-Flag tag||RG81601-NF|
|Rat CLU ORF mammalian expression plasmid, N-His tag||RG81601-NH|
|Rat CLU ORF mammalian expression plasmid, N-Myc tag||RG81601-NM|
|Rat CLU ORF mammalian expression plasmid, N-HA tag||RG81601-NY|
|Rat CLU natural ORF mammalian expression plasmid||RG81601-UT|
|Learn more about expression Vectors|
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.