|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat SULT1A1 ORF mammalian expression plasmid, C-GFPSpark tag||RG81238-ACG|
|Rat SULT1A1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG81238-ACR|
|Rat SULT1A1 ORF mammalian expression plasmid, N-GFPSpark tag||RG81238-ANG|
|Rat SULT1A1 ORF mammalian expression plasmid, N-OFPSpark / RFP tag||RG81238-ANR|
|Rat SULT1A1 ORF mammalian expression plasmid, C-Flag tag||RG81238-CF|
|Rat SULT1A1 ORF mammalian expression plasmid, C-His tag||RG81238-CH|
|Rat SULT1A1 ORF mammalian expression plasmid, C-Myc tag||RG81238-CM|
|Rat SULT1A1 ORF mammalian expression plasmid, C-HA tag||RG81238-CY|
|Rat SULT1A1 ORF mammalian expression plasmid, N-Flag tag||RG81238-NF|
|Rat SULT1A1 ORF mammalian expression plasmid, N-His tag||RG81238-NH|
|Rat SULT1A1 ORF mammalian expression plasmid, N-Myc tag||RG81238-NM|
|Rat SULT1A1 ORF mammalian expression plasmid, N-HA tag||RG81238-NY|
|Rat SULT1A1 Gene cDNA clone plasmid||RG81238-U|
|Rat SULT1A1 natural ORF mammalian expression plasmid||RG81238-UT|
|Learn more about expression Vectors|
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Particularly SULT1A1 (Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), a member of the sulfotransferase 1 subfamily, which is a major pathway for drug metabolism in humans. Humans have at least 10 functional SULT genes. There has been an explosion in information on sulfotransferase polymorphisms and their functional consequences. An Arg213His polymorphism in SULT1A1 has a strong influence on the level of enzyme protein and activity in platelets, which have been widely used for phenotyping. Statistically significant associations were observed between the SULT1A1 genotype (Arg213His) and age, obesity and certain neoplasias (mammary, pulmonary, esophageal and urothelial cancer). Furthermore, the polymorphism of the SULT1A1 may be closely associated with breast cancer.