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Human KIR2DL3 / CD158B2 / NKAT-2 Protein (His Tag)

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Human KIR2DL3 Protein Product Information
Synonym:CU464054.1, CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIRCL23, MGC129943, NKAT, NKAT2, NKAT2A, NKAT2B, p58
Protein Construction:A DNA sequence encoding the human KIR2DL3 (AAX23102.1) extracellular domain (Met 1-His 245) was fused with a polyhistidine tag at the C-terminus.
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human KIR2DL3 Protein QC Testing
Purity:> 98 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:His 22
Molecule Mass:The secreted recombinant human KIR2DL3 consists of 235 amino acids and has a predicted molecular mass of 25.9 kDa. As a result of glycosylation, the apparent molecular mass of rh KIR2DL3 is approximately 45 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human KIR2DL3 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Human KIR2DL3 Protein SDS-PAGE
Human KIR2DL3 / CD158B2 / NKAT-2 Protein (His Tag) SDS-PAGE
Other KIR2DL3 Recombinant Protein Products
KIR2DL3 (CD158b2) Background

Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. KIR2DL3 contains 2 Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.

Human KIR2DL3 (CD158b2) References
  • Selvakumar A., et al., 1997, Immunol. Rev. 155:183-196.
  • Wilson M.J., et al., 1997, Tissue Antigens 49:574-579.
  • Maenaka K., et al., 1999, Structure 7:391-398.
  • Vitale,M. et al., 2004, Int Immunol. 16 (10):1459-66.
  • Yu M.-C., et al., 2008, Nat. Immunol. 9:898-907.
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    Size / Price
    Catalog: 12828-H08H-50
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    AvailabilityIn StockShipping instructions
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.