|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat FSTL1 ORF mammalian expression plasmid, C-GFPSpark tag||RG80885-ACG|
|Rat FSTL1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80885-ACR|
|Rat FSTL1 ORF mammalian expression plasmid, C-Flag tag||RG80885-CF|
|Rat FSTL1 ORF mammalian expression plasmid, C-His tag||RG80885-CH|
|Rat FSTL1 ORF mammalian expression plasmid, C-Myc tag||RG80885-CM|
|Rat FSTL1 ORF mammalian expression plasmid, C-HA tag||RG80885-CY|
|Rat FSTL1 ORF mammalian expression plasmid, N-Flag tag||RG80885-NF|
|Rat FSTL1 ORF mammalian expression plasmid, N-His tag||RG80885-NH|
|Rat FSTL1 ORF mammalian expression plasmid, N-Myc tag||RG80885-NM|
|Rat FSTL1 ORF mammalian expression plasmid, N-HA tag||RG80885-NY|
|Rat FSTL1 Gene cDNA clone plasmid||RG80885-U|
|Rat FSTL1 natural ORF mammalian expression plasmid||RG80885-UT|
|Learn more about expression Vectors|
Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.