|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat FDPS ORF mammalian expression plasmid, C-GFPSpark tag||RG80771-ACG|
|Rat FDPS ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80771-ACR|
|Rat FDPS ORF mammalian expression plasmid, N-GFPSpark tag||RG80771-ANG|
|Rat FDPS ORF mammalian expression plasmid, N-OFPSpark / RFP tag||RG80771-ANR|
|Rat FDPS ORF mammalian expression plasmid, C-Flag tag||RG80771-CF|
|Rat FDPS ORF mammalian expression plasmid, C-His tag||RG80771-CH|
|Rat FDPS ORF mammalian expression plasmid, C-Myc tag||RG80771-CM|
|Rat FDPS ORF mammalian expression plasmid, C-HA tag||RG80771-CY|
|Rat FDPS ORF mammalian expression plasmid, N-Flag tag||RG80771-NF|
|Rat FDPS ORF mammalian expression plasmid, N-His tag||RG80771-NH|
|Rat FDPS ORF mammalian expression plasmid, N-Myc tag||RG80771-NM|
|Rat FDPS ORF mammalian expression plasmid, N-HA tag||RG80771-NY|
|Rat FDPS Gene cDNA clone plasmid||RG80771-U|
|Rat FDPS natural ORF mammalian expression plasmid||RG80771-UT|
|Learn more about expression Vectors|
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell.