|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat CCL6 ORF mammalian expression plasmid, C-GFPSpark tag||RG80721-ACG|
|Rat CCL6 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80721-ACR|
|Rat CCL6 ORF mammalian expression plasmid, C-Flag tag||RG80721-CF|
|Rat CCL6 ORF mammalian expression plasmid, C-His tag||RG80721-CH|
|Rat CCL6 ORF mammalian expression plasmid, C-Myc tag||RG80721-CM|
|Rat CCL6 ORF mammalian expression plasmid, C-HA tag||RG80721-CY|
|Rat CCL6 ORF mammalian expression plasmid, N-Flag tag||RG80721-NF|
|Rat CCL6 ORF mammalian expression plasmid, N-His tag||RG80721-NH|
|Rat CCL6 ORF mammalian expression plasmid, N-Myc tag||RG80721-NM|
|Rat CCL6 ORF mammalian expression plasmid, N-HA tag||RG80721-NY|
|Rat CCL6 Gene cDNA clone plasmid||RG80721-U|
|Rat CCL6 natural ORF mammalian expression plasmid||RG80721-UT|
|Learn more about expression Vectors|
Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears to contribute to the macrophage infiltration that is independent of other CC chemokines. C10 is a prominent chemokine expressed in the central nervous system in experimental inflammatory demyelinating disease, also acts as a potent chemotactic factor for the migration of these leukocytes to the brain. CCL6 may be a mediator released by microglia for cell-cell communication under physiological as well as pathological conditions of CNS. Additionally, the chemokine CCL6 may alter tumor behavior by relieving its growth factor dependency and by promoting invasiveness as a result of local tissue apoptosis.