|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat ADK ORF mammalian expression plasmid, C-GFPSpark tag||RG80662-ACG|
|Rat ADK ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80662-ACR|
|Rat ADK ORF mammalian expression plasmid, N-GFPSpark tag||RG80662-ANG|
|Rat ADK ORF mammalian expression plasmid, N-OFPSpark / RFP tag||RG80662-ANR|
|Rat ADK ORF mammalian expression plasmid, C-Flag tag||RG80662-CF|
|Rat ADK ORF mammalian expression plasmid, C-His tag||RG80662-CH|
|Rat ADK ORF mammalian expression plasmid, C-Myc tag||RG80662-CM|
|Rat ADK ORF mammalian expression plasmid, C-HA tag||RG80662-CY|
|Rat ADK ORF mammalian expression plasmid, N-Flag tag||RG80662-NF|
|Rat ADK ORF mammalian expression plasmid, N-His tag||RG80662-NH|
|Rat ADK ORF mammalian expression plasmid, N-Myc tag||RG80662-NM|
|Rat ADK ORF mammalian expression plasmid, N-HA tag||RG80662-NY|
|Rat ADK Gene cDNA clone plasmid||RG80662-U|
|Rat ADK natural ORF mammalian expression plasmid||RG80662-UT|
|Learn more about expression Vectors|
Adenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme adenosine kinase (ADK), which differ at their N-terminal ends, are found in mammalian cells. It has been shown that the two ADK isoforms differ only in their first exons and the promoter regions; hence they arise via differential splicing of their first exons with the other exons common to both isoforms. In adult brain, ADK is primarily present in astrocytes. Several lines of experimental evidence support a critical role of ADK in different types of brain injury associated with astrogliosis, which is also a prominent morphologic feature of temporal lobe epilepsy (TLE). It has been suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of TLE. Moreover, in vitro data suggest the existence of an additional layer of modulatory crosstalk between the astrocyte-based adenosine cycle and inflammation. ADK also contributes to CK homeostasis in vivo.