|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat VTN ORF mammalian expression plasmid, C-GFPSpark tag||RG80609-ACG|
|Rat VTN ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80609-ACR|
|Rat VTN ORF mammalian expression plasmid, C-Flag tag||RG80609-CF|
|Rat VTN ORF mammalian expression plasmid, C-His tag||RG80609-CH|
|Rat VTN ORF mammalian expression plasmid, C-Myc tag||RG80609-CM|
|Rat VTN ORF mammalian expression plasmid, C-HA tag||RG80609-CY|
|Rat VTN ORF mammalian expression plasmid, N-Flag tag||RG80609-NF|
|Rat VTN ORF mammalian expression plasmid, N-His tag||RG80609-NH|
|Rat VTN ORF mammalian expression plasmid, N-Myc tag||RG80609-NM|
|Rat VTN ORF mammalian expression plasmid, N-HA tag||RG80609-NY|
|Rat VTN Gene cDNA clone plasmid||RG80609-U|
|Rat VTN natural ORF mammalian expression plasmid||RG80609-UT|
|Learn more about expression Vectors|
Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.