|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Rat IL20 ORF mammalian expression plasmid, C-GFPSpark tag||RG80422-ACG|
|Rat IL20 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80422-ACR|
|Rat IL20 ORF mammalian expression plasmid, C-Flag tag||RG80422-CF|
|Rat IL20 ORF mammalian expression plasmid, C-His tag||RG80422-CH|
|Rat IL20 ORF mammalian expression plasmid, C-Myc tag||RG80422-CM|
|Rat IL20 ORF mammalian expression plasmid, C-HA tag||RG80422-CY|
|Rat IL20 Gene cDNA clone plasmid||RG80422-G|
|Rat IL20 ORF mammalian expression plasmid, N-Flag tag||RG80422-NF|
|Rat IL20 ORF mammalian expression plasmid, N-His tag||RG80422-NH|
|Rat IL20 ORF mammalian expression plasmid, N-Myc tag||RG80422-NM|
|Rat IL20 ORF mammalian expression plasmid, N-HA tag||RG80422-NY|
|Rat IL20 natural ORF mammalian expression plasmid||RG80422-UT|
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IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells.It has been shown that interleukin-20 transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.