|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat IL5 ORF mammalian expression plasmid, C-GFPSpark tag||RG80458-ACG|
|Rat IL5 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80458-ACR|
|Rat IL5 ORF mammalian expression plasmid, C-Flag tag||RG80458-CF|
|Rat IL5 ORF mammalian expression plasmid, C-His tag||RG80458-CH|
|Rat IL5 ORF mammalian expression plasmid, C-Myc tag||RG80458-CM|
|Rat IL5 ORF mammalian expression plasmid, C-HA tag||RG80458-CY|
|Rat IL5 Gene cDNA clone plasmid||RG80458-G|
|Rat IL5 ORF mammalian expression plasmid, N-Flag tag||RG80458-NF|
|Rat IL5 ORF mammalian expression plasmid, N-His tag||RG80458-NH|
|Rat IL5 ORF mammalian expression plasmid, N-Myc tag||RG80458-NM|
|Rat IL5 ORF mammalian expression plasmid, N-HA tag||RG80458-NY|
|Rat IL5 natural ORF mammalian expression plasmid||RG80458-UT|
|Learn more about expression Vectors|
Interleukin 5 (IL-5) is a member of the interleukin family with length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins / signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered as a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues, and can modulate eosinophil behavior at every stage from maturation to survival.