|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat PDCD1LG2 ORF mammalian expression plasmid, C-GFPSpark tag||RG80454-ACG|
|Rat PDCD1LG2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80454-ACR|
|Rat PDCD1LG2 ORF mammalian expression plasmid, C-Flag tag||RG80454-CF|
|Rat PDCD1LG2 ORF mammalian expression plasmid, C-His tag||RG80454-CH|
|Rat PDCD1LG2 ORF mammalian expression plasmid, C-Myc tag||RG80454-CM|
|Rat PDCD1LG2 ORF mammalian expression plasmid, C-HA tag||RG80454-CY|
|Rat PDCD1LG2 Gene cDNA clone plasmid||RG80454-G|
|Rat PDCD1LG2 ORF mammalian expression plasmid, N-Flag tag||RG80454-NF|
|Rat PDCD1LG2 ORF mammalian expression plasmid, N-His tag||RG80454-NH|
|Rat PDCD1LG2 ORF mammalian expression plasmid, N-Myc tag||RG80454-NM|
|Rat PDCD1LG2 ORF mammalian expression plasmid, N-HA tag||RG80454-NY|
|Rat PDCD1LG2 natural ORF mammalian expression plasmid||RG80454-UT|
|Learn more about expression Vectors|
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.