|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat IL20 ORF mammalian expression plasmid, C-GFPSpark tag||RG80422-ACG|
|Rat IL20 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80422-ACR|
|Rat IL20 ORF mammalian expression plasmid, C-Flag tag||RG80422-CF|
|Rat IL20 ORF mammalian expression plasmid, C-His tag||RG80422-CH|
|Rat IL20 ORF mammalian expression plasmid, C-Myc tag||RG80422-CM|
|Rat IL20 ORF mammalian expression plasmid, C-HA tag||RG80422-CY|
|Rat IL20 Gene cDNA clone plasmid||RG80422-G|
|Rat IL20 ORF mammalian expression plasmid, N-Flag tag||RG80422-NF|
|Rat IL20 ORF mammalian expression plasmid, N-His tag||RG80422-NH|
|Rat IL20 ORF mammalian expression plasmid, N-Myc tag||RG80422-NM|
|Rat IL20 ORF mammalian expression plasmid, N-HA tag||RG80422-NY|
|Rat IL20 natural ORF mammalian expression plasmid||RG80422-UT|
|Learn more about expression Vectors|
IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells.It has been shown that interleukin-20 transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.