|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Rat CD5 ORF mammalian expression plasmid, C-GFPSpark tag||RG80374-ACG|
|Rat CD5 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80374-ACR|
|Rat CD5 ORF mammalian expression plasmid, C-Flag tag||RG80374-CF|
|Rat CD5 ORF mammalian expression plasmid, C-His tag||RG80374-CH|
|Rat CD5 ORF mammalian expression plasmid, C-Myc tag||RG80374-CM|
|Rat CD5 ORF mammalian expression plasmid, C-HA tag||RG80374-CY|
|Rat CD5 Gene cDNA clone plasmid||RG80374-G|
|Rat CD5 ORF mammalian expression plasmid, N-Flag tag||RG80374-NF|
|Rat CD5 ORF mammalian expression plasmid, N-His tag||RG80374-NH|
|Rat CD5 ORF mammalian expression plasmid, N-Myc tag||RG80374-NM|
|Rat CD5 ORF mammalian expression plasmid, N-HA tag||RG80374-NY|
|Rat CD5 natural ORF mammalian expression plasmid||RG80374-UT|
|Learn more about expression Vectors|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.