|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat COLEC12 ORF mammalian expression plasmid, C-GFPSpark tag||RG80394-ACG|
|Rat COLEC12 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80394-ACR|
|Rat COLEC12 ORF mammalian expression plasmid, C-Flag tag||RG80394-CF|
|Rat COLEC12 ORF mammalian expression plasmid, C-His tag||RG80394-CH|
|Rat COLEC12 ORF mammalian expression plasmid, C-Myc tag||RG80394-CM|
|Rat COLEC12 ORF mammalian expression plasmid, C-HA tag||RG80394-CY|
|Rat COLEC12 Gene cDNA clone plasmid||RG80394-G|
|Rat COLEC12 ORF mammalian expression plasmid, N-Flag tag||RG80394-NF|
|Rat COLEC12 ORF mammalian expression plasmid, N-His tag||RG80394-NH|
|Rat COLEC12 ORF mammalian expression plasmid, N-Myc tag||RG80394-NM|
|Rat COLEC12 ORF mammalian expression plasmid, N-HA tag||RG80394-NY|
|Rat COLEC12 natural ORF mammalian expression plasmid||RG80394-UT|
|Learn more about expression Vectors|
CLP1, also known as COLEC12, is a scavenger receptor that displays several functions associated with host defense. It contains 1 C-type lectin domain and 3 collagen-like domains. CLP1 is strongly expressed in placenta and moderately expressed in heart, skeletal muscle, small intestine and lung. It promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. CLP1 mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. It binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. It binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). CLP1 may also play a role in the clearance of amyloid beta in Alzheimer disease.