|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat CD276 ORF mammalian expression plasmid, C-GFPSpark tag||RG80380-ACG|
|Rat CD276 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80380-ACR|
|Rat CD276 ORF mammalian expression plasmid, C-Flag tag||RG80380-CF|
|Rat CD276 ORF mammalian expression plasmid, C-His tag||RG80380-CH|
|Rat CD276 ORF mammalian expression plasmid, C-Myc tag||RG80380-CM|
|Rat CD276 ORF mammalian expression plasmid, C-HA tag||RG80380-CY|
|Rat CD276 Gene cDNA clone plasmid||RG80380-G|
|Rat CD276 ORF mammalian expression plasmid, N-Flag tag||RG80380-NF|
|Rat CD276 ORF mammalian expression plasmid, N-His tag||RG80380-NH|
|Rat CD276 ORF mammalian expression plasmid, N-Myc tag||RG80380-NM|
|Rat CD276 ORF mammalian expression plasmid, N-HA tag||RG80380-NY|
|Rat CD276 natural ORF mammalian expression plasmid||RG80380-UT|
|Learn more about expression Vectors|
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.