|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat CLEC1A ORF mammalian expression plasmid, C-GFPSpark tag||RG80212-ACG|
|Rat CLEC1A ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80212-ACR|
|Rat CLEC1A ORF mammalian expression plasmid, C-Flag tag||RG80212-CF|
|Rat CLEC1A ORF mammalian expression plasmid, C-His tag||RG80212-CH|
|Rat CLEC1A ORF mammalian expression plasmid, C-Myc tag||RG80212-CM|
|Rat CLEC1A ORF mammalian expression plasmid, C-HA tag||RG80212-CY|
|Rat CLEC1A Gene cDNA clone plasmid||RG80212-G|
|Rat CLEC1A ORF mammalian expression plasmid, N-Flag tag||RG80212-NF|
|Rat CLEC1A ORF mammalian expression plasmid, N-His tag||RG80212-NH|
|Rat CLEC1A ORF mammalian expression plasmid, N-Myc tag||RG80212-NM|
|Rat CLEC1A ORF mammalian expression plasmid, N-HA tag||RG80212-NY|
|Rat CLEC1A natural ORF mammalian expression plasmid||RG80212-UT|
|Learn more about expression Vectors|
CLEC1A, also known as CLEC-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC1A contains 1 C-type lectin domain and is expressed preferentially in dendritic cells. It may play a role in regulating dendritic cell function. CLEC1A gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splice variants have been described but their biological nature has not been determined. CLEC1A is found to be not only expressed in dendritic cells, but also in endothelial cells and in the latter aspect resembles the LOX-1 gene.