|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat IL27 ORF mammalian expression plasmid, C-GFPSpark tag||RG80201-ACG|
|Rat IL27 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80201-ACR|
|Rat IL27 ORF mammalian expression plasmid, C-Flag tag||RG80201-CF|
|Rat IL27 ORF mammalian expression plasmid, C-His tag||RG80201-CH|
|Rat IL27 ORF mammalian expression plasmid, C-Myc tag||RG80201-CM|
|Rat IL27 ORF mammalian expression plasmid, C-HA tag||RG80201-CY|
|Rat IL27 Gene cDNA clone plasmid||RG80201-G|
|Rat IL27 ORF mammalian expression plasmid, N-Flag tag||RG80201-NF|
|Rat IL27 ORF mammalian expression plasmid, N-His tag||RG80201-NH|
|Rat IL27 ORF mammalian expression plasmid, N-Myc tag||RG80201-NM|
|Rat IL27 ORF mammalian expression plasmid, N-HA tag||RG80201-NY|
|Rat IL27 natural ORF mammalian expression plasmid||RG80201-UT|
|Learn more about expression Vectors|
IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells and dendritic cells. IL-27 protein is also referred as the IL-12 p35-related protein, p28, is one subunit of a heterodimeric cytokine complex, and associates with another subunit EBI3 (EBV-induced gene 3), an IL-12 p40-related protein (IL-27B). IL-27 protein is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 protein has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy.