|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat IL10RB ORF mammalian expression plasmid, C-GFPSpark tag||RG80184-ACG|
|Rat IL10RB ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80184-ACR|
|Rat IL10RB ORF mammalian expression plasmid, C-Flag tag||RG80184-CF|
|Rat IL10RB ORF mammalian expression plasmid, C-His tag||RG80184-CH|
|Rat IL10RB ORF mammalian expression plasmid, C-Myc tag||RG80184-CM|
|Rat IL10RB ORF mammalian expression plasmid, C-HA tag||RG80184-CY|
|Rat IL10RB Gene cDNA clone plasmid||RG80184-G|
|Rat IL10RB ORF mammalian expression plasmid, N-Flag tag||RG80184-NF|
|Rat IL10RB ORF mammalian expression plasmid, N-His tag||RG80184-NH|
|Rat IL10RB ORF mammalian expression plasmid, N-Myc tag||RG80184-NM|
|Rat IL10RB ORF mammalian expression plasmid, N-HA tag||RG80184-NY|
|Rat IL10RB natural ORF mammalian expression plasmid||RG80184-UT|
|Learn more about expression Vectors|
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 receptor. IL10RB/IL-10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB/IL-10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.