|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat TIMP1 ORF mammalian expression plasmid, C-GFPSpark tag||RG80064-ACG|
|Rat TIMP1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80064-ACR|
|Rat TIMP1 ORF mammalian expression plasmid, C-Flag tag||RG80064-CF|
|Rat TIMP1 ORF mammalian expression plasmid, C-His tag||RG80064-CH|
|Rat TIMP1 ORF mammalian expression plasmid, C-Myc tag||RG80064-CM|
|Rat TIMP1 ORF mammalian expression plasmid, C-HA tag||RG80064-CY|
|Rat TIMP1 Gene cDNA clone plasmid||RG80064-M|
|Rat TIMP1 ORF mammalian expression plasmid, N-Flag tag||RG80064-NF|
|Rat TIMP1 ORF mammalian expression plasmid, N-His tag||RG80064-NH|
|Rat TIMP1 ORF mammalian expression plasmid, N-Myc tag||RG80064-NM|
|Rat TIMP1 ORF mammalian expression plasmid, N-HA tag||RG80064-NY|
|Rat TIMP1 natural ORF mammalian expression plasmid||RG80064-UT|
|Learn more about expression Vectors|
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.