|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat IFNA1 ORF mammalian expression plasmid, C-GFPSpark tag||RG80174-ACG|
|Rat IFNA1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80174-ACR|
|Rat IFNA1 ORF mammalian expression plasmid, C-Flag tag||RG80174-CF|
|Rat IFNA1 ORF mammalian expression plasmid, C-His tag||RG80174-CH|
|Rat IFNA1 ORF mammalian expression plasmid, C-Myc tag||RG80174-CM|
|Rat IFNA1 ORF mammalian expression plasmid, C-HA tag||RG80174-CY|
|Rat IFNA1 Gene cDNA clone plasmid||RG80174-G|
|Rat IFNA1 ORF mammalian expression plasmid, N-Flag tag||RG80174-NF|
|Rat IFNA1 ORF mammalian expression plasmid, N-His tag||RG80174-NH|
|Rat IFNA1 ORF mammalian expression plasmid, N-Myc tag||RG80174-NM|
|Rat IFNA1 ORF mammalian expression plasmid, N-HA tag||RG80174-NY|
|Rat IFNA1 natural ORF mammalian expression plasmid||RG80174-UT|
|Learn more about expression Vectors|
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus.Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.