|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat IL11 ORF mammalian expression plasmid, C-GFPSpark tag||RG80169-ACG|
|Rat IL11 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80169-ACR|
|Rat IL11 ORF mammalian expression plasmid, C-Flag tag||RG80169-CF|
|Rat IL11 ORF mammalian expression plasmid, C-His tag||RG80169-CH|
|Rat IL11 ORF mammalian expression plasmid, C-Myc tag||RG80169-CM|
|Rat IL11 ORF mammalian expression plasmid, C-HA tag||RG80169-CY|
|Rat IL11 Gene cDNA clone plasmid||RG80169-G|
|Rat IL11 ORF mammalian expression plasmid, N-Flag tag||RG80169-NF|
|Rat IL11 ORF mammalian expression plasmid, N-His tag||RG80169-NH|
|Rat IL11 ORF mammalian expression plasmid, N-Myc tag||RG80169-NM|
|Rat IL11 ORF mammalian expression plasmid, N-HA tag||RG80169-NY|
|Rat IL11 natural ORF mammalian expression plasmid||RG80169-UT|
|Learn more about expression Vectors|
IL11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.