|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat TNFRSF19 ORF mammalian expression plasmid, C-GFPSpark tag||RG80167-ACG|
|Rat TNFRSF19 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80167-ACR|
|Rat TNFRSF19 ORF mammalian expression plasmid, C-Flag tag||RG80167-CF|
|Rat TNFRSF19 ORF mammalian expression plasmid, C-His tag||RG80167-CH|
|Rat TNFRSF19 ORF mammalian expression plasmid, C-Myc tag||RG80167-CM|
|Rat TNFRSF19 ORF mammalian expression plasmid, C-HA tag||RG80167-CY|
|Rat TNFRSF19 Gene cDNA clone plasmid||RG80167-G|
|Rat TNFRSF19 ORF mammalian expression plasmid, N-Flag tag||RG80167-NF|
|Rat TNFRSF19 ORF mammalian expression plasmid, N-His tag||RG80167-NH|
|Rat TNFRSF19 ORF mammalian expression plasmid, N-Myc tag||RG80167-NM|
|Rat TNFRSF19 ORF mammalian expression plasmid, N-HA tag||RG80167-NY|
|Rat TNFRSF19 natural ORF mammalian expression plasmid||RG80167-UT|
|Learn more about expression Vectors|
Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.