|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat CD40 ORF mammalian expression plasmid, C-GFPSpark tag||RG80151-ACG|
|Rat CD40 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80151-ACR|
|Rat CD40 ORF mammalian expression plasmid, C-Flag tag||RG80151-CF|
|Rat CD40 ORF mammalian expression plasmid, C-His tag||RG80151-CH|
|Rat CD40 ORF mammalian expression plasmid, C-Myc tag||RG80151-CM|
|Rat CD40 ORF mammalian expression plasmid, C-HA tag||RG80151-CY|
|Rat CD40 Gene cDNA clone plasmid||RG80151-G|
|Rat CD40 ORF mammalian expression plasmid, N-Flag tag||RG80151-NF|
|Rat CD40 ORF mammalian expression plasmid, N-His tag||RG80151-NH|
|Rat CD40 ORF mammalian expression plasmid, N-Myc tag||RG80151-NM|
|Rat CD40 ORF mammalian expression plasmid, N-HA tag||RG80151-NY|
|Rat CD40 natural ORF mammalian expression plasmid||RG80151-UT|
|Learn more about expression Vectors|
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.