|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat TNFSF8 ORF mammalian expression plasmid, C-GFPSpark tag||RG80148-ACG|
|Rat TNFSF8 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80148-ACR|
|Rat TNFSF8 ORF mammalian expression plasmid, C-Flag tag||RG80148-CF|
|Rat TNFSF8 ORF mammalian expression plasmid, C-His tag||RG80148-CH|
|Rat TNFSF8 ORF mammalian expression plasmid, C-Myc tag||RG80148-CM|
|Rat TNFSF8 ORF mammalian expression plasmid, C-HA tag||RG80148-CY|
|Rat TNFSF8 Gene cDNA clone plasmid||RG80148-G|
|Rat TNFSF8 ORF mammalian expression plasmid, N-Flag tag||RG80148-NF|
|Rat TNFSF8 ORF mammalian expression plasmid, N-His tag||RG80148-NH|
|Rat TNFSF8 ORF mammalian expression plasmid, N-Myc tag||RG80148-NM|
|Rat TNFSF8 ORF mammalian expression plasmid, N-HA tag||RG80148-NY|
|Rat TNFSF8 natural ORF mammalian expression plasmid||RG80148-UT|
|Learn more about expression Vectors|
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. CD30L is a type-II membrane glycoprotein expressed on activated T cells, stimulated monocyte-macrophages, granulocytes, eosinophils, and some Burkitt-like lymphoma cell lines. CD30L is capable of transducing signals through CD30 on different CD30+ lymphoma cell lines, and mediates pleiotropic biologic effects including cell proliferation, activation, differentiation, as well as cell death by apoptosis. CD30-CD30 ligand interaction has been suggested to have a pathophysiologic role in malignant lymphomas, particularly Hodgkin disease, large cell anaplastic lymphomas and Burkitt lymphomas, and is also involved in activation and functioning of the T cell-dependent immune response. Thus, CD153 and its receptor CD30 are regarded as therapeutic targets in hematologic malignancies, autoimmune and inflammatory diseases.