|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat TNFSF4 ORF mammalian expression plasmid, C-GFPSpark tag||RG80146-ACG|
|Rat TNFSF4 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80146-ACR|
|Rat TNFSF4 ORF mammalian expression plasmid, C-Flag tag||RG80146-CF|
|Rat TNFSF4 ORF mammalian expression plasmid, C-His tag||RG80146-CH|
|Rat TNFSF4 ORF mammalian expression plasmid, C-Myc tag||RG80146-CM|
|Rat TNFSF4 ORF mammalian expression plasmid, C-HA tag||RG80146-CY|
|Rat TNFSF4 Gene cDNA clone plasmid||RG80146-G|
|Rat TNFSF4 ORF mammalian expression plasmid, N-Flag tag||RG80146-NF|
|Rat TNFSF4 ORF mammalian expression plasmid, N-His tag||RG80146-NH|
|Rat TNFSF4 ORF mammalian expression plasmid, N-Myc tag||RG80146-NM|
|Rat TNFSF4 ORF mammalian expression plasmid, N-HA tag||RG80146-NY|
|Rat TNFSF4 natural ORF mammalian expression plasmid||RG80146-UT|
|Learn more about expression Vectors|
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.