|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat CNTFR ORF mammalian expression plasmid, C-GFPSpark tag||RG80019-ACG|
|Rat CNTFR ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80019-ACR|
|Rat CNTFR ORF mammalian expression plasmid, C-Flag tag||RG80019-CF|
|Rat CNTFR ORF mammalian expression plasmid, C-His tag||RG80019-CH|
|Rat CNTFR ORF mammalian expression plasmid, C-Myc tag||RG80019-CM|
|Rat CNTFR ORF mammalian expression plasmid, C-HA tag||RG80019-CY|
|Rat CNTFR Gene cDNA clone plasmid||RG80019-M|
|Rat CNTFR ORF mammalian expression plasmid, N-Flag tag||RG80019-NF|
|Rat CNTFR ORF mammalian expression plasmid, N-His tag||RG80019-NH|
|Rat CNTFR ORF mammalian expression plasmid, N-Myc tag||RG80019-NM|
|Rat CNTFR ORF mammalian expression plasmid, N-HA tag||RG80019-NY|
|Rat CNTFR natural ORF mammalian expression plasmid||RG80019-UT|
|Learn more about expression Vectors|
Ciliary neurotrophic factor(CNTF) is a member of the cytokine family. It is a polypeptide hormone that have functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. It's actions appear to be restricted to the nervous system. Ciliary neurotrophic factor(CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracelluar CNTF binding subunit(CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF is also a survival factor for neurons of the peripheral sensory sympathetic, and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors.