|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat BMPR1B ORF mammalian expression plasmid, C-GFPSpark tag||RG80128-ACG|
|Rat BMPR1B ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80128-ACR|
|Rat BMPR1B ORF mammalian expression plasmid, C-Flag tag||RG80128-CF|
|Rat BMPR1B ORF mammalian expression plasmid, C-His tag||RG80128-CH|
|Rat BMPR1B ORF mammalian expression plasmid, C-Myc tag||RG80128-CM|
|Rat BMPR1B ORF mammalian expression plasmid, C-HA tag||RG80128-CY|
|Rat BMPR1B Gene cDNA clone plasmid||RG80128-G|
|Rat BMPR1B ORF mammalian expression plasmid, N-Flag tag||RG80128-NF|
|Rat BMPR1B ORF mammalian expression plasmid, N-His tag||RG80128-NH|
|Rat BMPR1B ORF mammalian expression plasmid, N-Myc tag||RG80128-NM|
|Rat BMPR1B ORF mammalian expression plasmid, N-HA tag||RG80128-NY|
|Rat BMPR1B natural ORF mammalian expression plasmid||RG80128-UT|
|Learn more about expression Vectors|
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective trasducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.