|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat MET ORF mammalian expression plasmid, C-GFPSpark tag||RG80004-ACG|
|Rat MET ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80004-ACR|
|Rat MET ORF mammalian expression plasmid, C-Flag tag||RG80004-CF|
|Rat MET ORF mammalian expression plasmid, C-His tag||RG80004-CH|
|Rat MET ORF mammalian expression plasmid, C-Myc tag||RG80004-CM|
|Rat MET ORF mammalian expression plasmid, C-HA tag||RG80004-CY|
|Rat MET Gene cDNA clone plasmid||RG80004-M|
|Rat MET ORF mammalian expression plasmid, N-Flag tag||RG80004-NF|
|Rat MET ORF mammalian expression plasmid, N-His tag||RG80004-NH|
|Rat MET ORF mammalian expression plasmid, N-Myc tag||RG80004-NM|
|Rat MET ORF mammalian expression plasmid, N-HA tag||RG80004-NY|
|Rat MET natural ORF mammalian expression plasmid||RG80004-UT|
|Learn more about expression Vectors|
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that has been shown to be overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.