|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat EFNA5 ORF mammalian expression plasmid, C-GFPSpark tag||RG80105-ACG|
|Rat EFNA5 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80105-ACR|
|Rat EFNA5 ORF mammalian expression plasmid, C-Flag tag||RG80105-CF|
|Rat EFNA5 ORF mammalian expression plasmid, C-His tag||RG80105-CH|
|Rat EFNA5 ORF mammalian expression plasmid, C-Myc tag||RG80105-CM|
|Rat EFNA5 ORF mammalian expression plasmid, C-HA tag||RG80105-CY|
|Rat EFNA5 Gene cDNA clone plasmid||RG80105-G|
|Rat EFNA5 ORF mammalian expression plasmid, N-Flag tag||RG80105-NF|
|Rat EFNA5 ORF mammalian expression plasmid, N-His tag||RG80105-NH|
|Rat EFNA5 ORF mammalian expression plasmid, N-Myc tag||RG80105-NM|
|Rat EFNA5 ORF mammalian expression plasmid, N-HA tag||RG80105-NY|
|Rat EFNA5 natural ORF mammalian expression plasmid||RG80105-UT|
|Learn more about expression Vectors|
Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A5/EFNA5 may function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Ephrin-A5/EFNA5 also serves as a cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.