|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat ERBB2 ORF mammalian expression plasmid, C-GFPSpark tag||RG80079-ACG|
|Rat ERBB2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80079-ACR|
|Rat ERBB2 ORF mammalian expression plasmid, C-Flag tag||RG80079-CF|
|Rat ERBB2 ORF mammalian expression plasmid, C-His tag||RG80079-CH|
|Rat ERBB2 ORF mammalian expression plasmid, C-Myc tag||RG80079-CM|
|Rat ERBB2 ORF mammalian expression plasmid, C-HA tag||RG80079-CY|
|Rat ERBB2 Gene cDNA clone plasmid||RG80079-M|
|Rat ERBB2 ORF mammalian expression plasmid, N-Flag tag||RG80079-NF|
|Rat ERBB2 ORF mammalian expression plasmid, N-His tag||RG80079-NH|
|Rat ERBB2 ORF mammalian expression plasmid, N-Myc tag||RG80079-NM|
|Rat ERBB2 ORF mammalian expression plasmid, N-HA tag||RG80079-NY|
|Rat ERBB2 natural ORF mammalian expression plasmid||RG80079-UT|
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Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.