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Human L-FABP / FABP1 Protein (His Tag)

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Human FABP1 Protein Product Information
Protein Construction:A DNA sequence encoding the human FABP1 (NP_001434.1) (Ser 2-Ile 127) was expressed, with a polyhistide tag at the N-terminus.
Expressed Host:E. coli
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human FABP1 Protein QC Testing
Purity:> 97 % as determined by SDS-PAGE
Endotoxin:Please contact us for more information.
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Met
Molecule Mass:The recombinant human FABP1 consisting of 137 amino acids and has a calculated molecular mass of 15.6 kDa. The apparent molecular mass of the protein is approximately 15 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 8.3
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human FABP1 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Other FABP1 Recombinant Protein Products
L-FABP/FABP1 Background

Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. FABP1 / FABPL binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. It forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. FABP1 / FABPL may be involved in intracellular lipid transport.

Human L-FABP/FABP1 References
  • Chen SH, et al.,1986, Somat Cell Mol Genet 12 (3): 303-6.
  • Weickert MO, et al.,2007, Am J Physiol Endocrinol Metab. 293(4): E1078-84.
  • Noiri,E. et al., 2009, Am J Physiol Renal Physiol  296 (4):F669-79.
  • Fisher,E. et al., 2007, Mol Genet Metab. 91 (3):278-84. 
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    Catalog: 12353-H07E-100
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