|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse MOG ORF mammalian expression plasmid, C-GFPSpark tag||MG51046-ACG|
|Mouse MOG ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG51046-ACR|
|Mouse MOG ORF mammalian expression plasmid, C-Flag tag||MG51046-CF|
|Mouse MOG ORF mammalian expression plasmid, C-His tag||MG51046-CH|
|Mouse MOG ORF mammalian expression plasmid, C-Myc tag||MG51046-CM|
|Mouse MOG ORF mammalian expression plasmid, C-HA tag||MG51046-CY|
|Mouse MOG Gene cDNA clone plasmid||MG51046-G|
|Mouse MOG ORF mammalian expression plasmid, N-Flag tag||MG51046-NF|
|Mouse MOG ORF mammalian expression plasmid, N-His tag||MG51046-NH|
|Mouse MOG ORF mammalian expression plasmid, N-Myc tag||MG51046-NM|
|Mouse MOG ORF mammalian expression plasmid, N-HA tag||MG51046-NY|
|Mouse MOG natural ORF mammalian expression plasmid||MG51046-UT|
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Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.