|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse FLT1 ORF mammalian expression plasmid, C-GFPSpark tag||MG51045-ACG|
|Mouse FLT1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG51045-ACR|
|Mouse FLT1 ORF mammalian expression plasmid, C-Flag tag||MG51045-CF|
|Mouse FLT1 ORF mammalian expression plasmid, C-His tag||MG51045-CH|
|Mouse FLT1 ORF mammalian expression plasmid, C-Myc tag||MG51045-CM|
|Mouse FLT1 ORF mammalian expression plasmid, C-HA tag||MG51045-CY|
|Mouse FLT1 Gene cDNA clone plasmid||MG51045-G|
|Mouse FLT1 ORF mammalian expression plasmid, N-Flag tag||MG51045-NF|
|Mouse FLT1 ORF mammalian expression plasmid, N-His tag||MG51045-NH|
|Mouse FLT1 ORF mammalian expression plasmid, N-Myc tag||MG51045-NM|
|Mouse FLT1 ORF mammalian expression plasmid, N-HA tag||MG51045-NY|
|Mouse FLT1 natural ORF mammalian expression plasmid||MG51045-UT|
|Learn more about expression Vectors|
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains seven Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.