|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse WIF1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50984-ACG|
|Mouse WIF1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50984-ACR|
|Mouse WIF1 ORF mammalian expression plasmid, C-Flag tag||MG50984-CF|
|Mouse WIF1 ORF mammalian expression plasmid, C-His tag||MG50984-CH|
|Mouse WIF1 ORF mammalian expression plasmid, C-Myc tag||MG50984-CM|
|Mouse WIF1 ORF mammalian expression plasmid, C-HA tag||MG50984-CY|
|Mouse WIF1 Gene cDNA clone plasmid||MG50984-G|
|Mouse WIF1 ORF mammalian expression plasmid, N-Flag tag||MG50984-NF|
|Mouse WIF1 ORF mammalian expression plasmid, N-His tag||MG50984-NH|
|Mouse WIF1 ORF mammalian expression plasmid, N-Myc tag||MG50984-NM|
|Mouse WIF1 ORF mammalian expression plasmid, N-HA tag||MG50984-NY|
|Mouse WIF1 natural ORF mammalian expression plasmid||MG50984-UT|
|Learn more about expression Vectors|
WIF1, also known as WIF-1 and wnt inhibitory factor 1, is a secreted protein which binds WNT proteins and inhibits their activities. It contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 may be involved in mesoderm segmentation and can be detected in fish, amphibia and mammals. WIF-1 is a recurrent target in human salivary gland oncogenesis. Downregulation of WIF1 takes part in the development and progression of pleomorphic adenomas. WIF1 also is a tumor suppressor, and has been found to be epigenetically silenced in various cancers, specifically in nonfunctioning pituitary tumors. WIF1 are expected to have molecular function (protein tyrosine kinase activity) and to localize in various compartments (extracellular space, extracellular region).