|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse NRN1 ORF mammalian expression plasmid, C-GFPSpark tag||MG52152-ACG|
|Mouse NRN1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG52152-ACR|
|Mouse NRN1 ORF mammalian expression plasmid, C-Flag tag||MG52152-CF|
|Mouse NRN1 ORF mammalian expression plasmid, C-His tag||MG52152-CH|
|Mouse NRN1 ORF mammalian expression plasmid, C-Myc tag||MG52152-CM|
|Mouse NRN1 ORF mammalian expression plasmid, C-HA tag||MG52152-CY|
|Mouse NRN1 Gene cDNA clone plasmid||MG52152-G|
|Mouse NRN1 ORF mammalian expression plasmid, N-Flag tag||MG52152-NF|
|Mouse NRN1 ORF mammalian expression plasmid, N-His tag||MG52152-NH|
|Mouse NRN1 ORF mammalian expression plasmid, N-Myc tag||MG52152-NM|
|Mouse NRN1 ORF mammalian expression plasmid, N-HA tag||MG52152-NY|
|Mouse NRN1 natural ORF mammalian expression plasmid||MG52152-UT|
|Learn more about expression Vectors|
Neuritin 1 (NRN1) is a member of neuritin family. Neuritin is a glycosylphosphatidylinositol- anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervous system and a population of small-diameter neurons in the dorsal root ganglia and was anterogradely and retrogradely transported. Neuritin message is induced by neuronal activity and by the activity-regulated neurotrophins BDNF, nerve growth factor (NGF) and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic hippocampal and cortical cultures. Thus, neuritin is considered as a downstream effector of activity-induced neurite outgrowth. In clinical, neuritin levels in diabetes were reduced in both dorsal root ganglia and sciatic nerve of rats, and these deficits were reversed in vivo by treatment with NGF. This manipulation of neuritin levels in diabetes may provide a potential target for the therapeutic intervention in the management of neuropathy.