|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse NAALADL1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50937-ACG|
|Mouse NAALADL1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50937-ACR|
|Mouse NAALADL1 ORF mammalian expression plasmid, C-Flag tag||MG50937-CF|
|Mouse NAALADL1 ORF mammalian expression plasmid, C-His tag||MG50937-CH|
|Mouse NAALADL1 ORF mammalian expression plasmid, C-Myc tag||MG50937-CM|
|Mouse NAALADL1 ORF mammalian expression plasmid, C-HA tag||MG50937-CY|
|Mouse NAALADL1 Gene cDNA clone plasmid||MG50937-G|
|Mouse NAALADL1 ORF mammalian expression plasmid, N-Flag tag||MG50937-NF|
|Mouse NAALADL1 ORF mammalian expression plasmid, N-His tag||MG50937-NH|
|Mouse NAALADL1 ORF mammalian expression plasmid, N-Myc tag||MG50937-NM|
|Mouse NAALADL1 ORF mammalian expression plasmid, N-HA tag||MG50937-NY|
|Mouse NAALADL1 natural ORF mammalian expression plasmid||MG50937-UT|
|Learn more about expression Vectors|
N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.