|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse SerpinI1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50926-ACG|
|Mouse SerpinI1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50926-ACR|
|Mouse SerpinI1 ORF mammalian expression plasmid, C-Flag tag||MG50926-CF|
|Mouse SerpinI1 ORF mammalian expression plasmid, C-His tag||MG50926-CH|
|Mouse SerpinI1 ORF mammalian expression plasmid, C-Myc tag||MG50926-CM|
|Mouse SerpinI1 ORF mammalian expression plasmid, C-HA tag||MG50926-CY|
|Mouse SerpinI1 Gene cDNA clone plasmid||MG50926-G|
|Mouse SerpinI1 ORF mammalian expression plasmid, N-Flag tag||MG50926-NF|
|Mouse SerpinI1 ORF mammalian expression plasmid, N-His tag||MG50926-NH|
|Mouse SerpinI1 ORF mammalian expression plasmid, N-Myc tag||MG50926-NM|
|Mouse SerpinI1 ORF mammalian expression plasmid, N-HA tag||MG50926-NY|
|Mouse SerpinI1 natural ORF mammalian expression plasmid||MG50926-UT|
|Learn more about expression Vectors|
Neuroserpin, also known as Protease inhibitor 12 and SERPINI1, is a secreted protein which belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons. Neuroserpin is predominantly expressed in the brain, and is expressed in the late stages of neurogenesis during the process of synapse formation. Overexpression of neuroserpin in an anterior pituitary corticotroph cell line results in the extension of neurite-like processes, suggesting that neuroserpin may play a role in cell communication, cell adhesion, and/or cell migration. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. Neuroserpin may also protect neurons from cell damage by tissue-type plasminogen activator. Defects of neuroserpin are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B).