|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Rat FLT1 ORF mammalian expression plasmid, C-GFPSpark tag||RG80101-ACG|
|Rat FLT1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80101-ACR|
|Rat FLT1 ORF mammalian expression plasmid, C-Flag tag||RG80101-CF|
|Rat FLT1 ORF mammalian expression plasmid, C-His tag||RG80101-CH|
|Rat FLT1 ORF mammalian expression plasmid, C-Myc tag||RG80101-CM|
|Rat FLT1 ORF mammalian expression plasmid, C-HA tag||RG80101-CY|
|Rat FLT1 Gene cDNA clone plasmid||RG80101-G|
|Rat FLT1 ORF mammalian expression plasmid, N-Flag tag||RG80101-NF|
|Rat FLT1 ORF mammalian expression plasmid, N-His tag||RG80101-NH|
|Rat FLT1 ORF mammalian expression plasmid, N-Myc tag||RG80101-NM|
|Rat FLT1 ORF mammalian expression plasmid, N-HA tag||RG80101-NY|
|Rat FLT1 natural ORF mammalian expression plasmid||RG80101-UT|
|Learn more about expression Vectors|
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains seven Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.