|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CD83 ORF mammalian expression plasmid, C-GFPSpark tag||MG50694-ACG|
|Mouse CD83 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50694-ACR|
|Mouse CD83 ORF mammalian expression plasmid, C-Flag tag||MG50694-CF|
|Mouse CD83 ORF mammalian expression plasmid, C-His tag||MG50694-CH|
|Mouse CD83 ORF mammalian expression plasmid, C-Myc tag||MG50694-CM|
|Mouse CD83 ORF mammalian expression plasmid, C-HA tag||MG50694-CY|
|Mouse CD83 Gene cDNA clone plasmid||MG50694-G|
|Mouse CD83 ORF mammalian expression plasmid, N-Flag tag||MG50694-NF|
|Mouse CD83 ORF mammalian expression plasmid, N-His tag||MG50694-NH|
|Mouse CD83 ORF mammalian expression plasmid, N-Myc tag||MG50694-NM|
|Mouse CD83 ORF mammalian expression plasmid, N-HA tag||MG50694-NY|
|Mouse CD83 natural ORF mammalian expression plasmid||MG50694-UT|
|Learn more about expression Vectors|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.