|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse ECM1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50331-ACG|
|Mouse ECM1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50331-ACR|
|Mouse ECM1 ORF mammalian expression plasmid, C-Flag tag||MG50331-CF|
|Mouse ECM1 ORF mammalian expression plasmid, C-His tag||MG50331-CH|
|Mouse ECM1 ORF mammalian expression plasmid, C-Myc tag||MG50331-CM|
|Mouse ECM1 ORF mammalian expression plasmid, C-HA tag||MG50331-CY|
|Mouse ECM1 Gene cDNA clone plasmid||MG50331-M|
|Mouse ECM1 ORF mammalian expression plasmid, N-Flag tag||MG50331-NF|
|Mouse ECM1 ORF mammalian expression plasmid, N-His tag||MG50331-NH|
|Mouse ECM1 ORF mammalian expression plasmid, N-Myc tag||MG50331-NM|
|Mouse ECM1 ORF mammalian expression plasmid, N-HA tag||MG50331-NY|
|Mouse ECM1 natural ORF mammalian expression plasmid||MG50331-UT|
|Learn more about expression Vectors|
Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.