|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse PLA2G1B ORF mammalian expression plasmid, C-GFPSpark tag||MG50329-ACG|
|Mouse PLA2G1B ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50329-ACR|
|Mouse PLA2G1B ORF mammalian expression plasmid, C-Flag tag||MG50329-CF|
|Mouse PLA2G1B ORF mammalian expression plasmid, C-His tag||MG50329-CH|
|Mouse PLA2G1B ORF mammalian expression plasmid, C-Myc tag||MG50329-CM|
|Mouse PLA2G1B ORF mammalian expression plasmid, C-HA tag||MG50329-CY|
|Mouse PLA2G1B Gene cDNA clone plasmid||MG50329-M|
|Mouse PLA2G1B ORF mammalian expression plasmid, N-Flag tag||MG50329-NF|
|Mouse PLA2G1B ORF mammalian expression plasmid, N-His tag||MG50329-NH|
|Mouse PLA2G1B ORF mammalian expression plasmid, N-Myc tag||MG50329-NM|
|Mouse PLA2G1B ORF mammalian expression plasmid, N-HA tag||MG50329-NY|
|Mouse PLA2G1B natural ORF mammalian expression plasmid||MG50329-UT|
|Learn more about expression Vectors|
Mouse phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein which belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic Phospholipase A2 / PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of Phospholipase A2 / PLA2G1B have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets. Mice lacking in Phospholipase A2 / PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.