|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse PCSK9 ORF mammalian expression plasmid, C-GFPSpark tag||MG50251-ACG|
|Mouse PCSK9 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50251-ACR|
|Mouse PCSK9 ORF mammalian expression plasmid, C-Flag tag||MG50251-CF|
|Mouse PCSK9 ORF mammalian expression plasmid, C-His tag||MG50251-CH|
|Mouse PCSK9 ORF mammalian expression plasmid, C-Myc tag||MG50251-CM|
|Mouse PCSK9 ORF mammalian expression plasmid, C-HA tag||MG50251-CY|
|Mouse PCSK9 Gene cDNA clone plasmid||MG50251-M|
|Mouse PCSK9 ORF mammalian expression plasmid, N-Flag tag||MG50251-NF|
|Mouse PCSK9 ORF mammalian expression plasmid, N-His tag||MG50251-NH|
|Mouse PCSK9 ORF mammalian expression plasmid, N-Myc tag||MG50251-NM|
|Mouse PCSK9 ORF mammalian expression plasmid, N-HA tag||MG50251-NY|
|Mouse PCSK9 natural ORF mammalian expression plasmid||MG50251-UT|
|Learn more about expression Vectors|
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.