|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse FGF10 ORF mammalian expression plasmid, C-GFPSpark tag||MG50196-ACG|
|Mouse FGF10 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50196-ACR|
|Mouse FGF10 ORF mammalian expression plasmid, C-Flag tag||MG50196-CF|
|Mouse FGF10 ORF mammalian expression plasmid, C-His tag||MG50196-CH|
|Mouse FGF10 ORF mammalian expression plasmid, C-Myc tag||MG50196-CM|
|Mouse FGF10 ORF mammalian expression plasmid, C-HA tag||MG50196-CY|
|Mouse FGF10 Gene cDNA clone plasmid||MG50196-M|
|Mouse FGF10 ORF mammalian expression plasmid, N-Flag tag||MG50196-NF|
|Mouse FGF10 ORF mammalian expression plasmid, N-His tag||MG50196-NH|
|Mouse FGF10 ORF mammalian expression plasmid, N-Myc tag||MG50196-NM|
|Mouse FGF10 ORF mammalian expression plasmid, N-HA tag||MG50196-NY|
|Mouse FGF10 natural ORF mammalian expression plasmid||MG50196-UT|
|Learn more about expression Vectors|
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF10 is required for normal branching morphogenesis. It may play a role in wound healing. Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG). ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.