|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse IL22RA2 ORF mammalian expression plasmid, C-GFPSpark tag||MG50102-ACG|
|Mouse IL22RA2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50102-ACR|
|Mouse IL22RA2 ORF mammalian expression plasmid, C-Flag tag||MG50102-CF|
|Mouse IL22RA2 ORF mammalian expression plasmid, C-His tag||MG50102-CH|
|Mouse IL22RA2 ORF mammalian expression plasmid, C-Myc tag||MG50102-CM|
|Mouse IL22RA2 ORF mammalian expression plasmid, C-HA tag||MG50102-CY|
|Mouse IL22RA2 Gene cDNA clone plasmid||MG50102-M|
|Mouse IL22RA2 natural ORF mammalian expression plasmid||MG50102-M-N|
|Mouse IL22RA2 ORF mammalian expression plasmid, N-Flag tag||MG50102-NF|
|Mouse IL22RA2 ORF mammalian expression plasmid, N-His tag||MG50102-NH|
|Mouse IL22RA2 ORF mammalian expression plasmid, N-Myc tag||MG50102-NM|
|Mouse IL22RA2 ORF mammalian expression plasmid, N-HA tag||MG50102-NY|
|Mouse IL22RA2 natural ORF mammalian expression plasmid||MG50102-UT|
|Learn more about expression Vectors|
Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type I I cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in placenta, spleen, breast, skin and lung. It is also detected in intestinal tract, testis, brain, heart and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important roles in immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptor have been discovered, a membrane-bound receptor and a soluble receptor.