|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse IL13RA1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50088-ACG|
|Mouse IL13RA1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50088-ACR|
|Mouse IL13RA1 ORF mammalian expression plasmid, C-Flag tag||MG50088-CF|
|Mouse IL13RA1 ORF mammalian expression plasmid, C-His tag||MG50088-CH|
|Mouse IL13RA1 ORF mammalian expression plasmid, C-Myc tag||MG50088-CM|
|Mouse IL13RA1 ORF mammalian expression plasmid, C-HA tag||MG50088-CY|
|Mouse IL13RA1 Gene cDNA clone plasmid||MG50088-M|
|Mouse IL13RA1 ORF mammalian expression plasmid, N-Flag tag||MG50088-NF|
|Mouse IL13RA1 ORF mammalian expression plasmid, N-His tag||MG50088-NH|
|Mouse IL13RA1 ORF mammalian expression plasmid, N-Myc tag||MG50088-NM|
|Mouse IL13RA1 ORF mammalian expression plasmid, N-HA tag||MG50088-NY|
|Mouse IL13RA1 natural ORF mammalian expression plasmid||MG50088-UT|
|Learn more about expression Vectors|
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.