|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse SCARB2 ORF mammalian expression plasmid, C-GFPSpark tag||MG50052-ACG|
|Mouse SCARB2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50052-ACR|
|Mouse SCARB2 ORF mammalian expression plasmid, C-Flag tag||MG50052-CF|
|Mouse SCARB2 ORF mammalian expression plasmid, C-His tag||MG50052-CH|
|Mouse SCARB2 ORF mammalian expression plasmid, C-Myc tag||MG50052-CM|
|Mouse SCARB2 ORF mammalian expression plasmid, C-HA tag||MG50052-CY|
|Mouse SCARB2 Gene cDNA clone plasmid||MG50052-M|
|Mouse SCARB2 ORF mammalian expression plasmid, N-Flag tag||MG50052-NF|
|Mouse SCARB2 ORF mammalian expression plasmid, N-His tag||MG50052-NH|
|Mouse SCARB2 ORF mammalian expression plasmid, N-Myc tag||MG50052-NM|
|Mouse SCARB2 ORF mammalian expression plasmid, N-HA tag||MG50052-NY|
|Mouse SCARB2 natural ORF mammalian expression plasmid||MG50052-UT|
|Learn more about expression Vectors|
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.