|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse ADAM9 ORF mammalian expression plasmid, C-GFPSpark tag||MG50044-ACG|
|Mouse ADAM9 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50044-ACR|
|Mouse ADAM9 ORF mammalian expression plasmid, C-Flag tag||MG50044-CF|
|Mouse ADAM9 ORF mammalian expression plasmid, C-His tag||MG50044-CH|
|Mouse ADAM9 ORF mammalian expression plasmid, C-Myc tag||MG50044-CM|
|Mouse ADAM9 ORF mammalian expression plasmid, C-HA tag||MG50044-CY|
|Mouse ADAM9 Gene cDNA clone plasmid||MG50044-M|
|Mouse ADAM9 ORF mammalian expression plasmid, N-Flag tag||MG50044-NF|
|Mouse ADAM9 ORF mammalian expression plasmid, N-His tag||MG50044-NH|
|Mouse ADAM9 ORF mammalian expression plasmid, N-Myc tag||MG50044-NM|
|Mouse ADAM9 ORF mammalian expression plasmid, N-HA tag||MG50044-NY|
|Mouse ADAM9 natural ORF mammalian expression plasmid||MG50044-UT|
|Learn more about expression Vectors|
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential therapeutic target in tumors where it is highly expressed. ADAM9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases involved in protein ectodomain shedding and cell-cell and cell-matrix interactions. ADAM-9 adhesive domain plays a role in regulating the motility of cells by interaction with beta1 integrins and modulates MMP synthesis.